Scientific articles published by the researchers of Barcelonaβeta Brain Research Center (BBRC), related to Alzheimer's disease, neuroimaging, memory and neurodegenerative diseases, among other fields.
Heeman F, Yaqub M, Hendriks J, van Berckel BNM, Collij LE, Gray KR, Manber R, Wolz R, Garibotto V, Wimberley C, Ritchie C, Barkhof F, Gispert JD, Vállez García D, Lopes Alves I, Lammertsma AA
Background: Despite its widespread use, the semi-quantitative standardized uptake value ratio (SUVR) may be biased compared with the distribution volume ratio (DVR). This bias may be partially...
Heeman F, Yaqub M, Hendriks J, van Berckel BNM, Collij LE, Gray KR, Manber R, Wolz R, Garibotto V, Wimberley C, Ritchie C, Barkhof F, Gispert JD, Vállez García D, Lopes Alves I, Lammertsma AA
Background: Despite its widespread use, the semi-quantitative standardized uptake value ratio (SUVR) may be biased compared with the distribution volume ratio (DVR). This bias may be partially...
Palmer WH, Telford M, Navarro A, Santpere G, Norman PJ
Herpesviruses are ubiquitous, genetically diverse DNA viruses, with long-term presence in humans associated with infrequent but significant pathology. Human leukocyte antigen (HLA) class I presents...
Brugulat-Serrat A, Chen Y, Demnitz N, Ashour A, Adrion E, Ilinca S, Kinchin I, Almirall-Sanchez A, Öz D, Karanja W, Pintado M, Rogers N, Browning A, Petkuté I, Lawlor B
No abstract available.
Palmer WH, Telford M, Navarro A, Santpere G, Norman PJ
Herpesviruses are ubiquitous, genetically diverse DNA viruses, with long-term presence in humans associated with infrequent but significant pathology. Human leukocyte antigen (HLA) class I presents...
Morenas-Rodríguez E, Li Y, Nuscher B, Franzmeier N, Xiong C, Suárez-Calvet M, Fagan AM, Schultz S, Gordon BA, Benzinger TLS, Hassenstab J, McDade E, Feederle R, Karch CM, Schlepckow K, Morris JC, Kleinberger G, Nellgard B, Vöglein J, Blennow K, Zetterberg H, Ewers M, Jucker M, Levin J, Bateman RJ, Haass C
Background: Therapeutic modulation of TREM2-dependent microglial function might provide an additional strategy to slow the progression of Alzheimer's disease. Although studies in animal models suggest...
Mielke MM, Aggarwal NT, Vila-Castelar C, Agarwal P, Arenaza-Urquijo EM, Brett B, Brugulat-Serrat A, DuBose LE, Eikelboom WS, Flatt J, Foldi NS, Franzen S, Gilsanz P, Li W, McManus AJ, van Lent DM, Milani SA, Shaaban CE, Stites SD, Sundermann E, Suryadevara V, Trani JF, Turner AD, Vonk JMJ, Quiroz YT, Babulal GM
Sex or gender differences in the risk of Alzheimer's disease and related dementias (ADRD) differ by world region, suggesting that there are potentially modifiable risk factors for intervention...
Pemberton HG, Collij LE, Heeman F, Bollack A, Shekari M, Salvadó G, Alves IL, Garcia DV, Battle M, Buckley C, Stephens AW, Bullich S, Garibotto V, Barkhof F, Gispert JD, Farrar G
Amyloid-β (Aβ) pathology is one of the earliest detectable brain changes in Alzheimer's disease (AD) pathogenesis. The overall load and spatial distribution of brain Aβ can be determined in vivo using...
Gonneaud J, Moreau I, Felisatti F, Arenaza-Urquijo E, Ourry V, Touron E, de la Sayette V, Vivien D, Chételat G
Introduction: Physical inactivity and female sex are independently associated with increased Alzheimer's disease (AD) lifetime risk. This study investigates the possible interactions between sex and...
Visser PJ, Reus LM, Gobom J, Jansen I, Dicks E, van der Lee SJ, Tsolaki M, Verhey FRJ, Popp J, Martinez-Lage P, Vandenberghe R, Lleó A, Molinuevo JL, Engelborghs S, Freund-Levi Y, Froelich L, Sleegers K, Dobricic V, Lovestone S, Streffer J, Vos SJB, Bos I
Background: Increased total tau (t-tau) in cerebrospinal fluid (CSF) is a key characteristic of Alzheimer's disease (AD) and is considered to result from neurodegeneration. T-tau levels, however, can...