Publicacions
Articles científics publicats pels investigadors del Barcelonaβeta Brain Research Center (BBRC), relacionats amb la malaltia d'Alzheimer, la neuroimatge, la memòria i les malalties neurodegeneratives, entre altres camps.
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Contador J, Suárez-Calvet M.
Blood-based biomarkers in the oldest old: towards Alzheimer's disease detection in primary care
The Lancet Regional Health Europe -
Vila-Castelar C, Akinci M, Palpatzis E, Aguilar-Dominguez P, Operto G, Kollmorgen G, Quijano-Rubio C, Blennow K, Zetterberg H, Falcon C, Fauria K, Gispert JD, Grau-Rivera O, Suárez-Calvet M, Arenaza-Urquijo EM.
Sex/gender effects of glial reactivity on preclinical Alzheimer's disease pathology
Mol Psychiatry.AbstractGlial reactivity may contribute to sex/gender differences in Alzheimer's disease (AD) pathophysiology. Here, we investigated the differential effect of cerebrospinal fluid (CSF) glial markers on AD...
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Vermunt L, Sutphen CL, Dicks E, de Leeuw DM, Allegri RF, Berman SB, Cash DM, Chhatwal JP, Cruchaga C, Day GS, Ewers M, Farlow MR, Fox NC, Ghetti B, Graff-Radford NR, Hassenstab J, Jucker M, Karch CM, Kuhle J, Laske C, Levin J, Masters CL, McDade E, Mori H, Morris JC, Perrin RJ, Preische O, Schofield PR, Suárez-Calvet M, Xiong C, Scheltens P, Teunissen CE, Visser PJ, Bateman RJ, Benzinger TLS, Fagan AM, Gordon BA, Tijms BM.
Axonal damage and inflammation response are biological correlates of decline in small-world values: a cohort study in autosomal dominant Alzheimer's disease
Brain Commun.AbstractThe grey matter of the brain develops and declines in coordinated patterns during the lifespan. Such covariation patterns of grey matter structure can be quantified as grey matter networks, which can...
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Lorenzini L, Maranzano A, Ingala S, Collij LE, Tranfa M, Blennow K, Di Perri C, Foley C, Fox NC, Frisoni GB, Haller S, Martinez-Lage P, Mollison D, O'Brien J, Payoux P, Ritchie C, Scheltens P, Schwarz AJ, Sudre CH, Tijms BM, Verde F, Ticozzi N, Silani V, Visser PJ, Waldman A, Wolz R, Chételat G, Ewers M, Wink AM, Mutsaerts H, Gispert JD, Wardlaw JM, Barkhof F.
Association of Vascular Risk Factors and Cerebrovascular Pathology With Alzheimer Disease Pathologic Changes in Individuals Without Dementia
NeurologyAbstractBackground and objectives: Vascular risk factors (VRFs) and cerebral small vessel disease (cSVD) are common in patients with Alzheimer disease (AD). It remains unclear whether this coexistence...
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Schöll M, Verberk IMW, Del Campo M, Delaby C, Therriault J, Chong JR, Palmqvist S, Alcolea D.
Challenges in the practical implementation of blood biomarkers for Alzheimer's disease
The Lancet Healthy LongevityAbstractBlood biomarkers have emerged as accessible, cost-effective, and highly promising tools for advancing the diagnostics of Alzheimer's disease. However, transitioning from cerebrospinal fluid biomarkers...
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Tristão-Pereira C, Fuster V, Lopez-Jimenez A, Fernández-Pena A, Semerano A, Fernandez-Nueda I, Garcia-Lunar I, Ayuso C, Sanchez-Gonzalez J, Ibanez B, Gispert JD, Cortes-Canteli M.
Subclinical atherosclerosis and brain health in midlife: Rationale and design of the PESA-Brain study
American Heart JournalAbstractRationale: Cognitive decline and dementia have been reportedly linked to atherosclerosis, the main cause of cardiovascular disease. Cohort studies identifying early brain alterations associated with...
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Rodríguez-Fernández B, Sánchez-Benavides G, Genius P, Minguillon C, Fauria K, De Vivo I, Navarro A, Molinuevo JL, Gispert JD, Sala-Vila A, Vilor-Tejedor N, Crous-Bou M.
Association between telomere length and cognitive function among cognitively unimpaired individuals at risk of Alzheimer's disease
Neurobiol AgingAbstractIntroduction: Leukocyte telomere length (LTL) is an objective biomarker of biological aging, and it is proposed to play a crucial role in Alzheimer's disease (AD) risk. We aimed at evaluating the...
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Falcon C, Montesinos P, Václavů L, Kassinopoulos M, Minguillon C, Fauria K, Cascales-Lahoz D, Contador J, Fernández-Lebrero A, Navalpotro I, Puig-Pijoan A, Grau-Rivera O, Kollmorgen G, Quijano-Rubio C, Molinuevo JL, Zetterberg H, Blennow K, Suárez-Calvet M, Van Osch MJP, Sanchez-Gonzalez J, Gispert JD.
Time-encoded ASL reveals lower cerebral blood flow in the early AD continuum
Alzheimers DementAbstractIntroduction: Cerebral blood flow (CBF) is reduced in cognitively impaired (CI) Alzheimer's disease (AD) patients. We checked the sensitivity of time-encoded arterial spin labeling (te-ASL) in...
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Pujol J, Blanco-Hinojo L, Persavento C, Martínez-Vilavella G, Falcón C, Gascón M, Rivas I, Vilanova M, Deus J, Gispert JD, Gómez-Roig MD, Llurba E, Dadvand P, Sunyer J.
Functional structure of local connections and differentiation of cerebral cortex areas in the neonate
NeuroImageAbstractNeuroimaging research on functional connectivity can provide valuable information on the developmental differentiation of the infant cerebral cortex into its functional areas. We examined healthy...
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Lázaro I, Grau-Rivera O, Suárez-Calvet M, Fauria K, Minguillón C, Shekari M, Falcón C, García-Prat M, Huguet J, Molinuevo JL, Gispert JD, Sala-Vila A.
Omega-3 blood biomarkers relate to brain glucose uptake in individuals at risk of Alzheimer's disease dementia
Alzheimers DementAbstractIntroduction: Brain glucose hypometabolism is a preclinical feature of Alzheimer's disease (AD). Dietary omega-3 fatty acids promote brain glucose metabolism, but clinical research is incipient...
