Publicacions
Articles científics publicats pels investigadors del Barcelonaβeta Brain Research Center (BBRC), relacionats amb la malaltia d'Alzheimer, la neuroimatge, la memòria i les malalties neurodegeneratives, entre altres camps.
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Pujol J, Martínez-Vilavella G, Gómez-Herrera L, Rivas I, Gómez-Roig MD, Llurba E, Blanco-Hinojo L, Cirach M, Persavento C, Querol X, Gascón M, Foraster M, Gispert JD, Falcón C, Deus J, Dadvand P, Sunyer J.
Unraveling the impact of prenatal air pollution for neonatal brain maturation
Environment InternationalAbstractEarly brain development is highly sensitive to environmental influences. While prenatal exposure to airborne particulate matter (PM2.5) has been broadly associated with harmful effects, PM2.5 also...
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van der Laan CM, Ip HF, Schipper M, Hottenga JJ, St Pourcain B, Zayats T, Pool R, Krapohl EML, Brikell I, Soler Artigas M, Cabana-Domínguez J, Nolte IM, Bolhuis K, Palviainen T, Zafarmand H, Gordon S, Aliev F, Burt SA, Wang CA, Saunders G, Karhunen V, Adkins DE, Border R, Peterson RE, Prinz JA, Thiering E, Vilor-Tejedor N, Ahluwalia TS, Allegrini A, Rimfeld K, Chen Q, Lu Y, Martin J, Bosch R, Ramos-Quiroga JA, Neumann A, Ensink J, Grasby KL, Morosoli JJ, Tong X, Marrington S, Scott JG, Shabalin AA, Corley R, Evans LM, Sugden K, Alemany S, Sass L, Vinding R, Ehli EA, Hagenbeek FA, Derks EM, Larsson H, Snieder H, Cecil C, Whipp AM, Korhonen T, Vuoksimaa E, Rose RJ, Uitterlinden AG, Haavik J, Harris JR, Helgeland Ø, Johansson S, Knudsen GPS, Njolstad PR, Lu Q, Rodriguez A, Henders AK, Mamun A, Najman JM, Brown S, Hopfer C, Krauter K, Reynolds CA, Smolen A, Stallings M, Wadsworth S, Wall TL, Eaves L, Silberg JL, Miller A, Havdahl A, Llop S, Lopez-Espinosa MJ, Bønnelykke K, Sunyer J, Arseneault L, Standl M, Heinrich J, Boden J, Pearson J, Horwood J, Kennedy M, Poulton R, Maes HH, Hewitt J, Copeland WE, Middeldorp CM, Williams GM, Wray N, Järvelin MR, McGue M, Iacono W, Caspi A, Moffitt TE, Whitehouse AJO, Pennell CE, Klump KL, Jiang C, Dick DM, Reichborn-Kjennerud T, Martin NG, Medland SE, Vrijkotte T, Kaprio J, Tiemeier H, Davey Smith G, Hartman CA, Oldehinkel AJ, Casas M, Ribasés M, Lichtenstein P, Lundström S, Plomin R, Bartels M, Nivard MG, Boomsma DI, Llonga N.
Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes
Nature GeneticsAbstractWe performed a genome-wide association meta-analysis (GWAMA) of 290,134 attention-deficit/hyperactivity disorder (ADHD) symptom measures of 70,953 unique individuals from multiple raters, ages and...
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Hok-A-Hin YS, Vermunt L, Peeters CFW, van der Ende EL, de Boer SCM, Meeter LH, de Houwer J, Seelaar H, van Swieten JC, Hu WT, Lleó A, Alcolea D, Engelborghs S, Sieben A, Chen-Plotkin A, Irwin DJ, van der Flier WM, Pijnenburg YAL, Teunissen CE, Del Campo M.
Large-scale CSF proteome profiling identifies biomarkers for accurate diagnosis of frontotemporal dementia
AbstractBackground: Diagnosis of Frontotemporal dementia (FTD) and its specific underlying neuropathologies (frontotemporal lobar degeneration; FTLD-Tau and FTLD-TDP) are challenging, and thus, fluid...
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Rodríguez-Fernández B, González-Escalante A, Genius P, E Evans T, Ortiz-Romero P, Minguillón C, Kollmorgen G, Ashton NJ, Zetterberg H, Blennow K, Gispert JD, Navarro A, Suárez-Calvet M, Sala-Vila A, Crous-Bou M, Vilor-Tejedor N.
Longitudinal association of shorter leukocyte telomere length with CSF biomarker dynamics across early Alzheimer's disease stages in at-risk individuals
EBioMedicineAbstractBackground: Short telomere length (TL), a hallmark of biological ageing, has been associated with an increased risk of Alzheimer's disease (AD), but its pathophysiological role remains unclear. This...
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Alraddadi A, Smalley JP, Alzahrani W, Saleh A, Al-Mansour F, He B, Cao TH, Jayne S, Dyer M, Hodgkinson JT, Jones DJL, Cowley SM, Macip S.
Targeted Degradation of Class 1 HDACs With PROTACs is Highly Effective at Inducing DLBCL Cell Death
EJHaemAbstractDespite the good options for the management of Diffuse large B-cell lymphoma (DLBCL), a significant percentage of patients either do not respond to current treatments or relapse after a short time...
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Osset-Malla M, Martínez-Velasco A, Sánchez-Benavides G, Buongiorno M, de la Sierra A, Shekari M, Minguillon C, Kollmorgen G, Quijano-Rubio C, Zetterberg H, Blennow K, García DV, Suárez-Calvet M, Gispert JD, Grau-Rivera O.
Blood pressure and Alzheimer's disease biomarkers in cognitively unimpaired adults: a multicenter study
The journal of prevention of Alzheimer's DiseaseAbstractBackground: Hypertension is a modifiable risk factor for dementia, potentially influencing Alzheimer's disease (AD) pathology. Understanding this relationship is essential for developing interventions...
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Oosthoek M, Vijverberg EGB, Blujdea ER, Veld SGJGI, Avilés MP, Zsadanyi SE, Hok-A-Hin YS, Visser A, van der Flier WM, Barkhof F, Del Campo M, Schut MC, Bejanin A, Alcolea D, Teunissen CE, Vermunt L.
CHIT1 and DDAH1 levels relate to amyloid-related imaging abnormalities risk profile in Alzheimer's disease patients
Alzheimer's Research & TherapyAbstractBackground: Amyloid-related imaging abnormalities (ARIA) are a common and potentially dangerous side effect in anti-amyloid therapies, creating a need for tools to assess ARIA risk. Several patient...
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Palmqvist S, Whitson HE, Allen LA, Suarez-Calvet M, Galasko D, Karikari TK, Okrahvi HR, Paczynski M, Schindler SE, Teunissen CE, Zetterberg H, Carrillo MC, Edelmayer RM, Mahinrad S, McAteer MB, Kahale LA, Pahlke S, Tampi MP.
Alzheimer's Association Clinical Practice Guideline on the use of blood-based biomarkers in the diagnostic workup of suspected Alzheimer's disease within specialized care settings
Alzheimer's & DementiaAbstractObjective and scope: A panel of clinicians, subject-matter experts, and guideline methodologists convened by the Alzheimer's Association conducted a systematic review and formulated evidence-based...
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Buongiorno M, Tur C, Giraldo DM, Cullell N, Krupinski J, Lanzillo R, Sánchez-Benavides G
Sleep and Risk of Multiple Sclerosis: Bridging the Gap Between Inflammation and Neurodegeneration via Glymphatic Failure
Brain SciencesAbstractEpidemiological studies identified insufficient and poor-quality sleep as independent risk factors for multiple sclerosis (MS). The glymphatic system, active during slow-wave sleep, clears brain waste...
